Pre-Analytical Errors in Haematology and Chemistry at Hayatabad Medical Complex Peshawar
Keywords:
Blood, Laboratory, Biochemistry, HematologyAbstract
OBJECTIVES
To determine the frequency of pre-analytical errors in haematology and chemistry at Hayatabad Medical Complex Peshawar.
METHODOLOGY
A descriptive cross-sectional study was conducted at the MTI/Hayatabad Medical Complex (HMC), Peshawar, from February to July 2022. Through the purposive sampling technique, 480 samples were collected. Each sample was tested to analyse and assess errors in haematology and chemistry. For statistical analysis, SPSS version 26.0 was used.
RESULTS
Four hundred eighty samples were studied during the project with the following pre-analytical errors, mainly 27.11% insufficient quantity, 22.91% clotted sample, 17.70% hemolysis, and 12.5% of the investigation were incorrect vacuum sealers or collection tubes. The analysis's error rate for the EDTA mix samples was 15.83, and 03.95% was the Hypervolumic sample in the study.
CONCLUSION
It was concluded that human error, technical error, and insufficient staff knowledge were the major errors in haematology and chemistry.
References
Plebani M, Sciacovelli L, Aita A, Padoan A, Chiozza ML. Quality indicators to detect pre-analytical errors in laboratory testing. Clin Chim Acta [Internet]. 2014;432:44–8
Chang J, Kim S, Yoo SJ, Park EJ, Um TH, Cho CR. Preanalytical errors in the central laboratory of a university hospital based on the analysis of year-round data. Clin Lab [Internet]. 2020;66(9)
Bhat V, Tiwari M, Chavan P, Kelkar R. Analysis of laboratory sample rejections in the pre-analytical stage at an oncology center. Clin Chim Acta [Internet]. 2012;413(15–16):1203–6
Lee NY. Reduction of pre-analytical errors in the clinical laboratory at the University Hospital of Korea through quality improvement activities. Clin Biochem [Internet]. 2019;70:24–9
Tapper MA, Pethick JC, Dilworth LL, McGrowder DA. Pre-analytical errors at the Chemical Pathology Laboratory of a teaching hospital. J Clin Diagn Res [Internet]. 2017;11(8):BC16–8
Plebani M, Sciacovelli L, Aita A, Pelloso M, Chiozza ML. Performance criteria and quality indicators for the pre-analytical phase. Clin Chem Lab Med [Internet]. 2015;53(6):943–8
Sciacovelli L, Lippi G, Sumarac Z, Del Pino Castro IG, Ivanov A, De Guire V, et al. Pre-analytical quality indicators in laboratory medicine: Performance of laboratories participating in the IFCC working group “Laboratory Errors and Patient Safety” project. Clin Chim Acta [Internet]. 2019;497:35–40
Shoaib M, Muzammil I, Bhutta ZA, Yaseen I, Munir H, Ali M, et al. Pre-analytical Errors and Rejection Criteria for Blood Samples in Hematology Laboratory. Journal of Agriculture, Food, Environment and Animal Sciences. 2020;1(1):39–49
Najat D. Prevalence of pre-analytical errors in clinical chemistry diagnostic labs in Sulaimani City of Iraqi Kurdistan. PLoS One [Internet]. 2017;12(1):e0170211
Narula A, Yadav SK, Jahan A, Verma A, Katyal A, Anand P, et al. Pre-analytical error in a hematology laboratory: an avoidable cause of compromised quality in reporting. Clin Chem Lab Med [Internet]. 2019;57(10):e262–4
Lima-Oliveira G, Volanski W, Lippi G, Picheth G, Guidi GC. Pre-analytical phase management: a review of the procedures from patient preparation to laboratory analysis. Scand J Clin Lab Invest [Internet]. 2017;77(3):153–63
Jafari E, Malekpour Afshar R, Aminzade R. Rates and reasons of laboratory sample rejection due to pre-analytical errors in clinical settings. Arch Iran Med [Internet]. 2022;25(3):166–70
Rajalakshmi V, Muthukrishnan R, Rajeswari K, Selvakumar AS. Identification of the types of pre-analytical errors in a hematology laboratory: 1 year study at ESIC hospital, Chennai. Trop J Path Micro. 2017;3:272–5
Cadamuro J, Lippi G, Meyer A, Ibarz M, Van Dongen-Lases E, Cornes M, et al. European survey on preanalytical sample handling-Part 2: Practices of European laboratories on monitoring and processing haemolytic, icteric and lipemic samples. On behalf of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group for the Preanalytical Phase (WG-PRE). Biochemia medica. 2019;29(2):334–45
Simundic AM, Baird G, Cadamuro J, Costelloe SJ, Lippi G. Managing hemolysed samples in clinical laboratories. Critical Reviews in Clinical Laboratory Sciences. 2020;57(1):1–21
Wan Azman WN, Koon OJ, Ismail TS. Hemolysed specimens: Major challenge for identifying and rejecting specimens in clinical laboratories. Oman medical journal. 2019;34
Heireman L, Van Geel P, Musger L, Heylen E, Uyttenbroeck W, Mahieu B. Causes, consequences and management of sample hemolysis in the clinical laboratory. Clin Biochem [Internet]. 2017;50(18):1317–22
Pande K, Dahal P, Pokharel L. Identification of types and frequency of pre-analytical errors in hematology laboratory at a tertiary hospital of Nepal. J Pathol Nepal [Internet]. 2021;11(1):1842–6
Downloads
Published
Deprecated: Function strftime() is deprecated in /home1/jwmiptpk/public_html/lib/pkp/lib/vendor/smarty/smarty/libs/plugins/modifier.date_format.php on line 81
2022-12-08
